“We were able to deliver the drug, called an LXR agonist, in eye drops,” says first author Abdoulaye Sene, PhD, a post-doctoral fellow in the Apte lab. “And we found that we could reverse the macular degeneration in the eye of an old mouse. That’s exciting because if we could use eye drops to deliver drugs that fight macular degeneration, we could focus therapy only on the eyes, and we likely could limit the side effects of drugs taken orally.”
The project is “a bold new research effort to revolutionize our understanding of the human mind and advance the president’s vision for creating jobs and building a thriving middle class by investing in research and development,” said a White House statement.
“Those are astronomical numbers. I’m floored,” said Dr. William Graf, a pediatric neurologist in New Haven and a professor at the Yale School of Medicine. He added, “Mild symptoms are being diagnosed so readily, which goes well beyond the disorder and beyond the zone of ambiguity to pure enhancement of children who are otherwise healthy.”
“Plants are all-natural sources of all things good for us, right? It turns out some of our favorite plant-based flavorings may do more harm than good.”
“A massive gene-hunting effort involving hundreds of scientists has identified 74 newly discovered regions of DNA that are associated with breast, ovarian and prostate cancers — diseases that strike about half a million Americans every year.”
“Sophisticated new prostate cancer tests are coming to market that might supplement the unreliable P.S.A. test, potentially saving tens of thousands of men each year from unnecessary biopsies, operations and radiation treatments.”
“Giving residents less time on duty and more time to sleep was supposed to lead to fewer medical errors. But the latest research shows that’s not the case. What’s going on?”
“Just about anyone who has gone to a pharmacy and paid for a prescription knows that a generic copy costs much less than the brand-name drug. The makers of those two versions of a drug, therefore, usually compete fiercely for market share and profits.”
A new study from Harvard Medical School has linked the overabundant salt intake to 2.3 million deaths worldwide in 2010 – from heart attacks, strokes and other heart-related problems, HealthDay News reported.
A case study reported in the March 21 issue of the New England Journal of Medicine shows how habitually drinking an extreme form of highly concentrated tea over almost 20 years created a hard-to-diagnose case of severe bone damage in a 47-year-old woman.